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Curriculum

Students pursuing a TBMH Master of Science or Doctor of Philosphy degree will take many of the same core courses. Information on our courses can be found below, while detailed plans of study can be found here:

TBMH 5004 Translational Biology, Medicine, and Health (8 credits)

The nature of the underlying processes of human health and disease and the context in which they occur.  Examines the processes of the normal vs. pathological lifespan trajectory of humans and animal models at the molecular, cellular, organ system, organismal, group and social levels.  Analysis of homeostatic processes throughout life’s stages and the genetic, environmental, behavioral and social drivers and interactions that lead to pathological outcomes.

TBMH 5105 & 5106 Professional Development and Ethics (2 credits each)

A one-year course for first year graduate students. The major focus is on essential skills that empower new graduate students to adjust to the new career demands, enhance their performance, and strategies to increase leadership skills, confidence, persistence, and communication skills. Additionally, responsible conduct in research training and ethical standards of science and in translational, biology, and health research are covered according to the NIH requirements.

TBMH 5304 Research Experience in Translational Biology, Medicine and Health (3 credits)

Research experience in biomedical, translational, and health sciences. Experimental design and methods, techniques and procedures, lab safety, data analysis and presentation. Serves as the basis for selection of a thesis advisor.

TBMH 5204 Seminar in Translational Biology, Medicine and Health (1 credit)

Weekly scientific research presentations from local and invited visiting scholars on current topics related to the biomedical, translational, and health sciences. Emerging technological and methodological trends. Recent conceptual advances, their relevance across specializations, and broader societal impact.

TBMH 5404 Scientific Logic and Analysis (1 credit)

Critical evaluation and discussion of primary health science and biomedical, research studies across the translational spectrum. Analysis of contemporary research problems and controversies, research design and methodology, and interdisciplinary approaches in translational science. Practicial experience with effective data presentation and peer-review. 

TBMH 5014 Fundamentals of Molecular Brain Science 

Comprehensive survey of brain and cognitive neuroscience across scales: normal function, pathology, therapeutics, and social and economic conditions.

TBMH 5024 Fundamentals of Cancer 

Comprehensive survey of neoplastic diseases across scales: genetic, molecular, cellular, tissue, organism, society. Causes, diagnosis and treatment of cancer. Social and economic aspects of cancer. 

TBMH 5034 Fundamentals of Public Health and Implementation Science 

The comprehensive survey course will include in-depth analysis of major medical and health discoveries on patient outcomes via translational research focused on scale-up and timely, effective delivery of new discoveries to targeted populations. Focus on epistemology, methodology, applications, and outcomes linked to translational science. Topics include implementation science related to: research design and strategies to speed the translation of proven health care interventions into practice; principles of adult learning and behavior change, systems and community-based participatory research; health services, patient centered research; impact assessment; health economics; health disparities; and health literacy applied to "Predictive, Preventive, Personalized, and Participatory Medicine”.

TBMH 5044 Fundamentals of Metabolic and Cardiovascular Science 

Comprehensive survey of metabolic and cardiovascular physiology, their interrelationship, and epidemiology and pathophysiology of cardiometabolic diseases with an emphasis on moving basic scientific discoveries into practical applications. 

TBMH 5054 Fundamentals of Immunity and Infectious Disease 

Comprehensive survey of human immunity, infectious agents and disease across scales: genetic, molecular, cellular, tissue, organism, society. Diagnosis, treatment, and prevention of infectious and immune diseases. Social and economic aspects of infection disease and immunity.

TBMH 5064 Fundamentals of Tissue Engineering and Reparative Medicine

Survey of the human lifespan, covering fundamentals of pre-natal and post-natal development, maturation and aging, and the capacity and mechanisms of tissue repair in a variety of organ systems. Emphasis on developmental psychology, developmentally regulated genetic/epigenetic interactions, morphogenesis, stem cell biology and regenerative medicine. Exemplars that span the translational continuum of key processes illustrating fundamental principles of development, aging and repair will be covered in an integrated manner. Impact of these advances on clinical approaches to developmental disorders, degenerative diseases and restorative therapies will be considered in the context of health care options, economic impact and in society at large.

TBMH 5074 Fundamentals of Cognitive Brain Science

This course will provide a fundamental understanding of the biological substrates responsible for the brain-behavior relationship. Topics in this course cover a broad selection of neuroscience ranging from the genetic and cellular level to how distributed processes across the entire brain contribute to the manifestation of high-order mental processes.

STAT 5674 - Methods in Biostatistics

Statistical principles and methods required for effective clinical trial and clinical experiment design and analysis. Topics include graphical and numerical exploratory data analysis, and comparative tests of categorical, ordinal, and continuous data, simple, multiple linear and logistic regression analysis, design of experiments and sampling theory. Additional topics include diagnostic tests, relative risk, odd ratio, and estimation of effective dose. Students will learn to properly interpret output from statistical software.

STAT 5605/06 - Biometry

5605: The normal distribution, estimation, hypothesis testing, simple linear regression, and one-way analysis of variance with applications to the biological sciences. 5606: Experimental design, nested and factorial analysis of variance, linear regression and correlation, and the use of SAS, with applications to the biological sciences. I

STAT 5615/16 - Statistics in Research

Concepts in statistical inference, including basic probability, estimation, and test of hypothesis, point and interval estimation and inferences; categorical data analysis; simple linear regression; and one-way analysis of variance. 5616: Multiple linear regression; multi-way classification analysis of variance; randomized block designs; nested designs; and analysis of covariance. One year of Calculus.

CS 5424 (GBCB 5424) - Computational Cell Biology

Use of mathematical models (nonlinear ordinary differential equations and stochastic processes) and simulation algorithms to explore the complex feedback circuits that control the behavior of living cells. Concepts and techniques from dynamical systems theory, bifurcation analysis, numerical methods, SBML (systems biology makeup language) and Matlab programming. Applications in gene regulatory networks, cell cycle control, circadian rhythms, cell signaling.

ALS 5115 – Nutrition, Digestion, Absorption, and Metabolism of Nutrients in Animals Including Humans
BCHM 5204 - Molecular Biology of Eukaryotic Gene Expression
BCHM 5224 - Protein Structure and Function
BIOL 5404 - Neuroethology
BIOL 5434 - Behavioral Endocrinology
BIOL 5564 - Adv Infectious Disease Ecology
BIOL 5624G - Advanced Microbial Genetics
BIOL 5734 - Advanced Inflammation Biology
BIOL 5884 - Molecular Biology of the Cell
BMES 5054 - Quantitative Cell Physiology
BMES 5184 - Injury Physiology
BMES 5314 - Introduction to Regenerative Medicine
BMES 5424 - Fundamentals of Tissue Structure, Function, and Replacement
BMES 5554 - Biomedical Signal and Image Processing
BMES 6514 - Medical Imaging II
BMVS 5305 (VM 9095) - Veterinary Oncology
BMVS 5624 - Molecular Virology
BMVS 6714 - Frontiers in Immunology in Health & Disease
CHEM 6564 - Bioorganic Principles of Medicinal Chemistry
ECON 6004 - Strategic Behavior
HD 5134 - Contemporary Issues in Aging
HD 5634 - Legislation and Policy in Human Development
HNFE 5144 - Molecular Aspects of Nutrition and Disease
HNFE 5146- Molecular Aspects of Diet and Cancer
HNFE 5724 (PHS 5024) - Epidemiology
NEUR 5034G- Advanced Diseases of the Nervous System
NEUR 5514G- Advanced Neuroimmunology
PSYC 5344 -Cognitive Psychology
PSYC 5374 - Health Psychology
TBMH 5094- Grant Writing and Ethics